The nature of thrombin and anti-thrombin

The role of thrombin and thrombin inhibitors in coronary angioplasty.

Anti-thrombin III activity in cerebrovascular accidents.

UNLABELLED Cerebrovascular accidents are commonly due to occlusive or haemorrhagic lesions. The present prospective study was planned to find out role of antithrombin in possible etiopathological process, which might predispose an individual for stroke. METHOD Biological activity of antithrombin III was done by the method as described by Innerfield et al (1976). Immunological estimation of an...

Appropriate Anti-Thrombotic/Anti-Thrombin Therapy for Thrombotic Lesions

Managing coronary thrombus is a challenging task and requires adequate knowledge of the various antithrombotic agents available. In this article, we will briefly analyze the risk-benefit profile of antithrombotic agents, with critical analysis of the scientific evidence available to support their use. Since thrombus consists of platelets and coagulation cofactors, an effective antithrombotic st...

by Antithrombin Interfere with the Inactivation of Thrombin the Antiphospholipid Syndrome That Identification of Anti-Thrombin Antibodies in

The effect of heparin adsorbed on Sepharose-lysine on the inactivation of thrombin by anti-thrombin III [proceedings].

The role of heparin in promoting the reaction between the plasma inhibitor, antithrombin I l l , and several proteolytic enzymes involved in blood coagulation is not clearly understood. Rosenberg and his colleagues (see, for example, Rosenberg & Damus, 1973; Highsmith & Rosenberg, 1974) have claimed that heparin binding modifies the shape of the anti-thrombin I I I molecule, thus exposing a vul...